promoter (redirected from Gene promoter)

promoter /pro·mo·ter/ (pro-mo´ter)

1. a segment of DNA usually occurring upstream from a gene coding region and acting as a controlling element in the expression of that gene.

2. a substance in a catalyst that increases its rate of activity.

3. a type of epigenetic carcinogen that promotes neoplastic growth only after initiation by another substance.

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pro·mot·er (pr-mtr)

n.

1. A substance that increases the activity of a catalyst.

2. A DNA molecule to which RNA polymerase binds, initiating the transcription of mRNA.

3. A chemical that may promote carcinogenicity or mutagenicity.

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promoter

[-mō′tər]

Etymology: L, promovere, to move forward

1 a DNA sequence that initiates transcription of the genetic code.

2 a cocarcinogen that encourages cells altered by initiators to reproduce more rapidly than normal, increasing the probability of malignant transformation. Examples include chlorophenothane (DDT), phenobarbital, saccharin, sunlight, and some chemicals in cigarette smoke. The effects of promoters are sometimes reversible.

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promoter

a specific DNA sequence to which RNA polymerase binds and signals where RNA synthesis (transcription) should begin.

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internal promoter

a class of enhancers which are gene-specific sequences that increase transcription.

promoter region

the non-coding nucleotide sequence at the transcription start region that is characterized by the presence of a number of conserved or consequence sequences.

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Patient discussion about Gene promoter.

Q. I am interested in social service. So what can I do to promote a healthy pregnancy?

A. Hi friend, once you're pregnant, a regular checkup is the key. Your health professional might want to monitor your baby's growth and watch for problems that can only be detected by checking your blood pressure, urine, and blood regularly. Anything you do that harms your body harms your fetus. Take special care: To avoid: tobacco smoking, alcohol, drugs, chemicals, radiation (as from X-rays), and sources of infection. Keep your body temperature from getting too high [over 100.4° (38°)] by treating any fevers with acetaminophen (such as Tylenol) and avoiding exercise or activity that overheats you. Also avoid high-temperature hot tubs and saunas. Take extra-good care of yourself while you're pregnant. Everything healthy you do for your body benefits your growing fetus. Rest when you need it, eat well, and exercise regularly.