Each chromosome end contains one to three var genes followed by a group of rif, stevor and other gene families
These predicted topologies differ markedly from the well-conserved pattern of 12 transmembrane helices characteristic of the SNF gene family, although they are consistent with the topologies reported among the eight amino acid transporter gene families
expressed across animal phyla (6-15 transmembrane helices: Saier, 2000).
Brandhorst, Jack Chen, and Karl Bergeron are among 200 researchers who have learned that many of the gene families
in the sea urchin, a simple spiny marine animal, are the same as these in the human and other complex vertebrates.
The PAR solicits applications to utilize the newly generated methodologies and reagents, such as the dones and sequence information, to identify and characterize genes, gene families
, and gene networks that control developmental and cellular events.
Sequence comparisons provide an understanding of the evolution of gene families
, describe molecular basis of adaptation and elucidate patterns of gene regulation and protein evolution.
Maybe there are gene families
that should be followed together.
The database combines proprietary immunohistochemistry data, obtained by using specific antibodies to determine protein localization in normal and diseased human tissues, with manually curated data covering more than 2,000 human genes from eight gene families
This is especially true of rapidly evolving gene families
, which may be the most important in distinguishing us from the great apes (see "Nature," v.
The new cluster provides increased power and scalability as we expand our chemogenomics platform to support parallel drug design in multiple gene families
Intron phases are fully conserved among all 14 human members and among members of the rodent kallikrein gene families
In addition, biopanned gene families
serve as the optimal breeding stock for Diversa's proprietary GeneReassembly(TM) evolution methods which physically blend related genes to create complex libraries of gene variants.
The plasmids exhibit significant genetic redundancy and carry 175 paralogous gene families
, most of of unknown function.