Furthermore, characterization of the alpha-tubulin gene family in Ceratopteris will ultimately help to answer questions specifically related to the origin and function of gene families
in organisms with large genomes.
Up to 20 of those genes may be selected from outside the eight gene families
specifically targeted for inclusion.
Vertex's software development efforts are now being expanded in the area of gene families
, with novel applications that enable analysis of a chemical library for selectivity among clusters of similar protein targets, and comparison of multiple libraries based on a single protein target.
Intron phases are fully conserved among all 14 human members and among members of the rodent kallikrein gene families
The plasmids exhibit significant genetic redundancy and carry 175 paralogous gene families
, most of of unknown function.
Statistical Methods for Detecting Functional Divergence of Gene Families
Fei said that the duplication contributed to adding additional members of gene families
that are involved in regulating important kiwifruit characteristics, like fruit vitamin C, flavonoid and carotenoid metabolism.
The team's work identified a variety of gene families
that may have future impact on improving cacao trees and fruit either by enhancing their attributes or providing protection from fungal diseases and insects that effect cacao trees.
Researchers mostly from multinational drug companies, but also universities describe compound design methods for generating small molecules that interact with important biological targets in eight major gene families
The discipline makes it possible to probe into the phylogenetic origins of gene families
and how they have been altered as species rose higher; eventually these gene structures and relative functions can be compared to those of humans, says NCT deputy director James K.
With the introduction of these library siRNA sets, researchers now have an off-the-shelf, high throughput RNAi solution that covers broad gene families
That makes the microRNA gene family comparable in size to other gene families
with a role in regulating gene activity.