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Gene Knockout Technique

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Gene Knockout Technique
An experimental technique used in genetics in which a normal gene is replaced by a defective gene either at the exact same chromosomal site—hence, the normal gene is ‘knocked out’ by the defective gene—as occurs with the yeast genome, or the DNA is inserted at random sites, as occurs in mammalian cells


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Group II intron-mediated gene disruption offers advantages over the laborious traditional gene knockout techniques such as randomly integrated transposons and cumbersome recombination methods," commented Keith Jolliff, Global Marketing Manager of Molecular Biology at Sigma-Aldrich.
Title - "The Development of a Novel Gene Knockout Technique Utilizing RNA Interference" --Aaron Kuan (Horace Greeley HS) Category - Environmental Science.
 
 
 
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