MMP9

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MMP9

A gene on chromosome 20q12-q13 that encodes matrix metalloproteinase 9, which degrades collagens IV and V, gelatins I and V, and fibronectin. It is thought to play a key role in local proteolysis of the extracellular matrix and in leukocyte migration, and may play a role in osteoclastic resorption of bone.

Molecular pathology
Defects in MMP9 increase susceptibility to intervertebral disc disease and lumbar disc herniation; MMP9 defects cause metaphyseal anadysplasia type 2.
References in periodicals archive ?
One of the most contentious decisions Peter Gelb made early in his tenure as general manager of the Met, where he arrived in 2006 as a modernising agent, was replacing the ornate Zeffirelli Tosca with a starker, grittier, more sexually explicit staging by Luc Bondy in 2009.
Jordan Gelb was recognized to the Financial Times 401 Top Retirement Advisors list for 2017.
Barbara Gelb, of charity Together for Short Lives, which gathered the palliative care data, said: "A child can deteriorate quickly.
We believe this is the first time the phenomenon has been observed using a human induced pluripotent stem cell model of the disease," said Bruce Gelb.
Howe Gelb sings on Gemma Ray's 2014 album Milk for the Motors but this concert was a one-off, curated by the Sage for the festival.
So Gelb was revised, eliminating the Netherlands except for the Maastricht Appendix, a small tail of Dutch territory that lay in the path of the Wehrmacht's advance.
FCC Enforcement Bureau Chief Travis LeBlanc intends to name Lisa Gelb as deputy chief and chief of staff of the bureau.
Thompson is the son of Cindy Gelb Grabner and Myron Thompson and the grandson of Joan and Vic Gelb, a past board chair of the Cleveland Jewish News.
The Advantage Group announced Stuart Gelb as has been named Commercial Finance Director at its mortgage financing subsidiary, Mortgage Advantage.
It's the performing arts equivalent of what sports teams do, to keep the bond strong between teams and their fanbase," says Peter Gelb, the Met's general manager.
Gelb as chief financial officer of its GoldPoint Partners private-equity business.
It will be led by healthcare com- munications professional based in GCC Petra Gelb.