Tetracyclines are a class of antibiotics which inhibit the catalytic activity of human collagenases and gelatinases
, especially MMPs.
An increase in the expression of gelatinases
in tumour cells in patients diagnosed with renal carcinoma was demonstrated.
activities appeared as clear bands against a blue background.
All bacterial isolates from the Nile tilapia culture water were subjected to the tests of virulence factor expression, with the help of the following exoenzymes: gelatinase
(GEL), elastase (Elas), caseinase (CAS), lipase (LIP), phospholipase (Phos) and haemolytic activity ([beta]-hemolysis in sheep blood) ([beta]-hem), following the methodologies of Rust, Messing, and Iglewski (1994), Rodrigues, Ribeiro, Alves, and Hofer (1993) and Furniss and Donovan (1979).
Miller, "Serum gelatinase
B, TIMP-1 and TIMP-2 levels in multiple sclerosis.
MMP-2, MMP-3, MMP-9, MMP-13, and MT1-MMP have all been identified in neuronal nuclei and gelatinases
(MMP-2 and MMP-9) and MMP-3 have been implicated in the progression of infarct volume and neuronal death in animal models of stroke and ischemic stroke patients [9,16,18, 23, 29-33].
, stromelysin-3, matrilysin, MT1-MMP , and stromelysin-1  are considered the most closely associated to the invasive phenotype.
, endonuclease and Vascular Endothelial Growth Factor during development and regression of swine luteal tissue.
In the present study, we compared the selectivity of SalA on collagenases and gelatinases
which are two kinds of MMPs that play important roles in aortic remodeling.
Unemori EN, Hibbs MS, Amento EP (1991) Constitutive expression of a 92kD gelatinase
(type V collagenase) by rheumatoid synovial fibroblasts and its induction in normal human fibroblasts by inflammatory cytokines.
We assessed putative MMP activity using gelatinase
activity in organ homogenates with the EnzChek gelatinase
assay kit (Invitrogen, Carlsbad, CA).
2010) have studied gelatinases
MMP-2 and MMP9 in both normal tissues and the ones with benign and malignant lesions in different species, including dogs, since MMPs are proteolytic enzymes capable of degrading components of connective tissue, such as the ECM, during tissue remodeling, which occurs in physiologic and pathologic conditions (EGEBLAD & WERB, 2002; MOOK et al.