gelatinase(redirected from Gelatinase a)
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Pepsin B; a metalloproteinase that hydrolyzes gelatin and a number of types of collagen. See: pepsin.
Metalloproteinases that cleave gelatin, or nondenatured collagen. Two forms of gelatinase, A and B, have been identified. Gelatinase A (MMP-2) has a molecular weight of about 72,000, and gelatinase B (MMP-9) has a molecular weight of about 92,000. Both are involved in cancer angiogenesis and metastasis and are blocked by a variety of naturally occurring and synthetic inhibitors.