gel filtration chromatography


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Related to gel filtration chromatography: Affinity chromatography, Ion exchange chromatography

gel fil·tra·tion

separation of molecular sizes by passage of a mixture through columns of beads of cross-linked dextrans or similar relatively inert material of a well-defined pore size range; the larger the molecule, the less time it spends in the interior of the beads, thus emerging earlier from the column than smaller molecules.

gel filtration chromatography

A type of column chromatography in which chemicals are separated via pores according to their molecular size.
See also: chromatography
References in periodicals archive ?
125]I binding (5); (c) ultrafiltration (6); (d) gel filtration chromatography (2); and (e) protein G affinity chromatography (5).
The molecular weight of this complex was determined by gel filtration chromatography, as described below.
1 shows that samples giving such recoveries contained 10-40% high-molecular weight PRL as determined by gel filtration chromatography.