Gaucher's cells


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Gaucher's cells

large, foamy macrophages characteristic of Gaucher's disease which accumulate in many tissues; they result from accumulated glucocerebroside due to deficiency in β-glucocerebrosidase.
References in periodicals archive ?
NIMH investigators, working with scientists at the Whitehead Institute in Boston, have transferred the normal gene into Gaucher's cells with a type 2 mutation and corrected the enzyme deficiency in tissue culture.