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gastrointestinal stromal tumor |
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gastrointestinal stromal tumor GIST Surgical pathology A nonmucosal GI tumor most common in the stomach Clinical Benign–leiomyoma or malignant–leiomyosarcoma, determined histologically by ↑ mitotic activity and bizarre cells,
findings seen in aggressive lesions. See Leiomyoma, Leiomyosarcoma. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Initially approved in 2001, Glivec, a single transduction inhibitor, is now available in over 80 countries worldwide and is indicated for the treatments of chronic myelocytic leukemia and gastrointestinal stromal tumor. Gastrointestinal stromal tumor, or GIST, is an unusual but highly lethal form of cancer. In this study, AMG 706 showed encouraging clinical activity in patients with advanced high-dose imatinib-resistant gastrointestinal stromal tumors (GIST). |
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