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bowel perforation |
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bowel perforation Gastrointestinal perforation GI disease Complete penetration of the intestinal wall resulting in bacterial contamination of the abdominal cavity/peritonitis How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Gastrointestinal perforations, ulcers and bleeding (PUB) events were evaluated as an exploratory endpoint, although it was expected that these results would be confounded by GPA and low-dose aspirin use. Entry criteria for these studies permitted enrollment of patients with active Helicobacter pylori infection, baseline gastroduodenal erosions, prior history of an upper gastrointestinal perforation, ulcer, or bleed (PUB), and/or age (>=)65 years. As in the pivotal Phase III study, although uncommon, the incidence of gastrointestinal perforation may be increased by the addition of Avastin to chemotherapy (two cases, 2 percent). |
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