gastrins


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gas·trins

(gas'trinz),
Hormones secreted in the pyloric-antral mucosa of the mammalian stomach that stimulate secretion of HCl by the parietal cells of the gastric glands; there are three main types: big gastrin (34 aminoacyl residues), little gastrin (17 residues), and minigastrin (14 residues), as well as sulfated derivatives. The C-terminal pentapeptide is also seen in cholecystokinin and cerulein.
[G. gastēr, stomach, + -in]

gas·trins

(gas'trinz)
Hormones secreted in the pyloric-antral mucosa of the mammalian stomach that stimulate secretion of HCl by the parietal cells of the gastric glands; a competitive inhibitor of gastrins is cholecystokinin.
[G. gastēr, stomach, + -in]

gas·trins

(gas'trinz)
Hormones secreted in the pyloric-antral mucosa of the mammalian stomach.
[G. gastēr, stomach, + -in]
References in periodicals archive ?
In clinical chemistry, the only well-indicated routine use of gastrin assays is in the diagnosis of gastrinomas, i.
The diagnosis was ascertained by increased serum concentrations of amidated gastrin, increased basal as well as pentagastrin-stimulated gastric acid secretion, gastroduodenoscopy, selective blood sampling from the portal vein (for gastrin measurements), abdominal computed tomography scanning, and somatostatin analog (octreotide) scintigraphy.
The median amidated gastrin concentration in normal serum was 10.
Long term omeprazole therapy in peptic ulcer disease: gastrin, endocrine cell growth and gastritis.
5] Nonstandard abbreviations: MTC, medullary thyroid carcinoma; MEN, multiple endocrine neoplasia; CT, calcitonin; and GT, gastrin.
1), whereas CCK-B receptors do not discriminate between sulfated and nonsulfated CCK-peptides or between CCK and gastrin peptides (for review, see references 1-3).
The plasma samples were stored at -20 [degrees]C until the measurement of gastrin and CCK.
Although several high-titer and high-affinity antisera were C-terminal directed (1559, 1560, 1564, 8007, and 8011), they all cross-reacted with gastrin peptides to a degree making them useless for plasma measurement.
Processing-independent assays have been useful as second-line assays for a few gastrinomas with truly normal or only slightly increased plasma concentrations of amidated gastrins (27, 38).
Clearance and acid-stimulating action of human big and little gastrins in duodenal ulcer subjects.
Results showed PL-induced rats had gastric mucosal damage, lesion ulcer, over-expression of acidity, gastrin and [H.
Gastrin is a linear peptide hormone produced by gastrin cells, having regulatory functions of acute gastric acid secretion as well as the gastric epithelial cell population (Kovac et al.