Ganglioside

ganglioside /gan·glio·side/ (gang´gle-o-sid) any of a group of glycosphingolipids found in the central nervous system tissues and having the basic composition ceramide-glucose-galactose-N -acetylneuraminic acid. The form GM1 accumulates in tissues in GM1 gangliosidoses and the form GM2 in GM2 gangliosidoses.

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gan·gli·o·side (gnggl--sd)

n.

Any of a group of glycosphingolipids chemically similar to the cerebrosides, found principally in the surface membrane of nerve cells and in the spleen.

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Ganglioside

A fatty (lipid) substance found within the brain and nerve cells.

Mentioned in: Tay-Sachs Disease

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ganglioside

a class of galactose-containing cerebrosides found in central nervous system tissues; they are glycolipids of the basic composition ceramide-glucose-galactose-N-acetyl neuraminic acid. The form GM₁ accumulates in tissues in generalized gangliosidosis as observed in Friesian cattle, dogs and cats. The form GM₂ accumulates in a similar disease of Yorkshire pigs, dogs and cats.