gamma-glutamyl transferase

gamma-glutamyl transferase

Gamma-glutamyl transpeptidase Lab medicine An enzyme that catalyzes the transfer of a γ-glutamyl group from glutathione or γ-glutamyl peptide to another peptide or amino acid; GGT is located on the cell membrane and microsomal fractions and is involved in amino acid transport across cell membranes; GGT is highest in the liver–GGT is the best single screening assay for detecting latent or chronic liver disease–eg, CA; in hepatobiliary diseases, a 10-fold + ↑ in GGT is seen in liver cancer, hepatic metastases, and PBC; a 4-fold + ↑ in GGT is seen in chronic active hepatitis, intrahepatic cholestasis, alcoholic hepatitis, extrahepatic biliary obstruction, and inactive cirrhosis.

gamma-glutamyl transferase

An enzyme widely distributed in body tissues and released into the blood when tissue, especially liver tissue, is damaged. Increased levels occur in liver damage from any cause. Measurements can be used as an index of alcohol abuse. Increased blood levels may sometimes occur without liver cell damage.
References in periodicals archive ?
The biochemical parameters such as aspartate transaminase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), lactate dehydrogenase (LDH), total bilirubin (TBIL), and direct bilirubin (DBIL) were evaluated at the initial time of admission to the hospital.
The results of blood tests were as follows: aspartate aminotransferase, 91 U/L; alanine aminotransferase, 66 U/L; gamma-glutamyl transferase, 447 U/L; zinc-protoporphyrin levels, 3.
Individuals with a high gamma-glutamyl transferase level also had a higher risk of subclinical carotid atherosclerosis, but this became nonsignificant after adjustment for metabolic variables.
The chemistry panel was within normal limits except for high levels of alanine transaminase and gamma-glutamyl transferase (65 [micro]/l and 72 [micro]/l; the reference ranges were 5 to 55 [micro]/l and 9 to 64 [micro]/l, respectively).
3]) 194000 133000 113000 Aspartate aminotransferase (U/L) 169 396 592 1228 Alanine aminotransferase (U/L) 641 541 616 1538 Alkaline phosphatase (U/L) 909 1209 1753 1695 Gamma-glutamyl transferase (U/L) 212 Total bilirubin (mg/dL) 2.
In the study, 36% of nivolumab-treated patients had serious adverse reactions; and 41% had grade 3 and 4 adverse reactions, the most common included an increase in gamma-glutamyl transferase in almost 4%, and diarrhea in 3.
It's called gamma-glutamyl transferase and raised levels predict stroke risk accurately.
Plasma biochemical analyte concentrations were not significantly different for calcium, amylase, uric acid, gamma-glutamyl transferase, bile acids, glucose, creatine kinase, total solids, cholesterol, triglycerides, or alkaline phosphatase levels before and after 14 days of treatment with meloxicam.
321; aspartate aminotransferase (AST): 59 U/L (5-40 U/L); alanine aminotransferase (ALT): 321 U/L (5-40 U/L); alkaline phosphatase (ALP): 154 U/L (35-125 U/L); gamma-glutamyl transferase (GGT): 168 U/L (10-45 U/L); lactate dehydrogenase (LDH): 556 U/L (200-450 U/L); blood urea nitrogen (BUN): 25 mg/dL (15-44 mg/dL); and creatinine: 0.
2 mg/L) and liver enzyme levels (aspartate aminotransferase 44 IU/L, gamma-glutamyl transferase 58 IU/L).
7 gm/dl, normal white count and platelet, normal C-reactive protein, alkaline phosphatase (ALP) 750 U/L, aspartate transaminase (AST) 169 U/L, alanine transaminase (ALT) 210 U/L, gamma-glutamyl transferase (GGT) 813 U/L, total bilirubin 13.
Objective Serum gamma-glutamyl transferase (GGT) is a marker for alcohol consumption and hepatobiliary diseases.

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