GTPase


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GTPase

enzyme activity that catalyzes the hydrolysis of guanosine triphosphate to guanosine diphosphate and orthophosphate.

GTPase

guanosine triphosphatase.
References in periodicals archive ?
Xin Zhang presents his chemistry thesis, presented to the California Institute of Technology, on Multistate GTPase Control Co-translational Protein Targeting, which is concerned with protein behavior at the molecular level.
048 RND2, SEMA4D neurons Abbreviations: ACER2, alkaline ceramidase 2; FUT4, fucosyltransferase 4; GCNT1, glucosaminyl (N-acetyl) transferase 1, core 2; MAN1B1, mannosidase, alpha, class 1B, member 1; NEU1, sialidase 1 (lysosomal sialidase); RND2, Rho family GTPase 2; SEMA4D, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D; SGPL1, sphingosine-1-phosphate lyase 1; ST8SIA4, ST8 alpha-N-acetyl-neuraminide alpha-2, 8-sialyltransferase 4; TNFAIP3, tumor necrosis factor, alpha-induced protein 3; TNFR1, tumor necrosis factor binding protein 1.
Anti-metastasis effects of gallic acid on gastric cancer cells involves inhibition of NF-kappaB activity and downregulation of PI3K/AKT/small GTPase signals.
Five differentially methylated regions [T-box 3 (TBX3) [4]; solute carrier family 38, member 10 (MGC15523); (sex determining region Y)-box 14 (SOX14); CDC42 effector protein (Rho GTPase binding) 1 (CDC42EP1); and sialophorin (SPN)] were selected, and differential methylation was confirmed by using EpiTYPER analysis as previously described (23).
The GTPase activity was reduced in the W07-toxin treated mice enterocytes which was found to be increased in presence of ouabain, a non-specific inhibitor of GTPase.
PHI is a small GTPase of the Rho family with effects on cell growth, morphogenesis, cell motility, cytokinesis, trafficking, and organization of cell cytoskeleton, cell motility, transformation, and metastasis.
Oncogenes and tumor suppressor genes in thyroid tumors Contributory genetic Neoplasm abnormalities Autonomously TSH receptor-activating functioning mutation; Gs-a mutation thyroid nodule decreasing GTPase activity Nodular goiter Many nodules are (colloid nodules) monoclonal, but precise gene abnormalities are unknown Follicular adenoma RAS mutations Papillary thyroid BRAF (V600E) activating carcinoma mutation; RET rearrange- ments (RET/PTC); NTRK1 rearrangements (TRK); 14q13.
ROP2 GTPASE IS REQUIRED FOR PROPER ATFH5 LOCALIZATION IN ARABIDOPSIS THALIANA.
EFL GTPase in cryptomonads and the distribution of EFL and EF-1[alpha] in chromalveolates.
Rho GTPase signalling pathways in the morphological changes associated with apoptosis.
Ethanol impairs Rho GTPase signaling and differentiation of cerebellar granule neurons in a rodent model of fetal alcohol syndrome.