GNB3

(redirected from GTP-binding regulatory protein beta-3 chain)

GNB3

A gene on chromosome 12p13 that encodes a beta subunit of a heterotrimeric guanine nucleotide-binding protein (G protein), which regulates signal transduction between receptors and effectors.

Molecular pathology
A single-nucleotide polymorphism in GNB3 is associated with essential hypertension and obesity.