ALG11

(redirected from GT8)

ALG11

A gene on chromosome 13q14.2 that encodes GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase, an enzyme localised to the cytosolic side of the endoplasmic reticulum that catalyses the transfer of the 4th and 5th mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol, resulting in the production of Man5GlcNAc2-PP-dolichol.

Molecular pathology
ALG11 is mutated in congenital disorder of glycosylation type Ip (CDGIp).
References in periodicals archive ?
A recent computational analysis of these sequences suggested that they may be conformationally similar to the glycosyltransferase GT8 family.
The sales figures include the sell-out demand for its DB11 model and special vehicles including the Vanquish Zagato and Aston Martin Vantage GT8, said a statement.
Aston Martin Holdings (UK) Ltd, the producer of luxury handcrafted sports cars, today announced that it sold 5,117 sports cars last year amid sell-out demand for its DB11 model and special vehicles including the Vanquish Zagato and Aston Martin Vantage GT8.
Cars such as the Vantage GT8 and Vantage GT12 confirmed that our customers love raw, racebred models, but we also knew there was an opportunity to create cars that offer a sharper performance focus but stop short of those truly hard-core, special series models.
Aston Martin president and chief executive, Dr Andy Palmer said: "Cars such as the Vantage GT8 and Vantage GT12 confirmed that our customers love raw, race-bred models, but we also knew there was an opportunity to create cars that offer a sharper performance focus but stop short of those truly hard-core, special series models.
We have also become world leaders in ultra-low volume projects with cars such as the One-77, Lagonda Taraf and Aston Martin Vulcan, while the Vantage GT12 and Vantage GT8 show how far we can take our series production models.
The legendary British sports car manufacturer also gave its Vantage GT8 - the lightest and most powerful V8-powered Vantage ever built - its first UK public runs at Goodwood, driven in Saturday's timed run category by Aston Martin Racing works driver, Darren Turner.
Just 150 examples of the Vantage GT8 will be produced, each priced from PS165,000.
Auto Business News-April 19, 2016--Aston Martin launches GT8
VersaDri 11 Canada has introduced the GT8 multifunctional drill rig--the result of more than three years of research and product development.
The company has provided eleven GT26 turbines and one GT8 turbine in Spain.