O3FAR1

(redirected from GT01)

O3FAR1

A gene on chromosome 10q23.33 that encodes a member of the rhodopsin family of G protein-coupled receptors that is a receptor for medium- and long-chain free fatty acids. O3FAR1 mediates a robust anti-inflammatory response, especially in macrophages and fat cells, by inhibiting TAK1 through a beta-arrestin 2 (ARRB2/TAB1)-dependent effect but independent of the G(q)/G(11)-coupled pathway. O3FAR1 mediates potent insulin-sensitising and antidiabetic effects by repressing macrophage-induced tissue inflammation.
References in periodicals archive ?
2] was GT01 (HSD co china) the particle diameter of GT01 is 180-250 [micro]m which is small enough for suspension but large enough for settlement by gravity.
2g/50 cc) was the optimum dosage of GT01 under the experimental condition in terms of catalytic oxidation reta.
Table 1 Trials to Criterion for Both Components of the Multiple Schedule During Phases 1-3 SS# Phase 1 Phase 2 Phase 3 G R G R G R MI01 159 55 48 46 49 46 MI02 307 113 48 573 65 109 MI03 270 57 44 49 55 45 MI04 114 60 59 81 56 48 MI05 257 55 53 50 47 51 GT01 133 52 43 51 44 45 GT02 79 66 44 44 44 46 GT03 51 54 45 45 53 47 GT04 218 56 48 45 54 54 GT05 196 51 45 44 47 46 GP01 156 60 45 45 45 47 GP02 305 53 48 97 50 50 GP03 200 82 111 60 69 91 GP04 262 57 47 135 58 47 GP05 115 58 49 50 51 49 ST01 50 46 53 69 70 47 ST02 53 53 53 49 58 55 ST03 63 46 59 47 50 53 ST04 64 65 59 48 55 62 ST05 60 49 50 50 50 53 SP01 44 48 47 63 45 55 SP02 97 74 45 51 49 50 SP03 44 50 49 46 54 48 SP04 50 53 49 44 58 51 SP05 48 44 381 236 48 48 Note.