CHST4

(redirected from GST3)

CHST4

A gene on chromosome 16q22.2 that encodes a sulfotransferase which catalyses the transfer of sulfate to residues within mucin-associated glycans. These glycans serve as L-selectin ligands, which are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing to sites of inflammation.

Molecular pathology
CHST4 is expressed in colonic mucinous adenocarcinoma.
References in periodicals archive ?
Z = 4,369 - 0,925 x BPK1 - 2,6156 x GST1 + 16,8242 x TP1 + 4,5762 x IK1 + 2,6439 x GP1 + 0,9115 x SPK1 - 20,0507 x TVP/T1 + 5,3164 x NP/T1 + 39,0135 x TVP/P1 + 5,9507 x GST2 + 7,2504 x TP2 - 16,7569 x IK2 + 18,8240 x GP2 + 7,8331 x TVP/T2 - 12,2667 x NP/T2 - 41,6082 x TVP/P2 + 1,1088 x GST3 - 26,2628 x TP3 + 8,6205 x IK3 + 54,9958 x GP3 + 18,0501 x TVP/T3 + 9,7489 x NP/T3 - 4,1720 x BP3 - 7,0197 x TVP/ P3 - 5,8053 x GP/T3.