GZMB

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GZMB

A gene on chromosome 14q11.2 that encodes an enzyme necessary for target cell lysis in cell-mediated immune responses, and which is linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis. GZMB cleaves caspase-3, -7, -9 and -10, activating enzymes that mediate apoptosis.
References in periodicals archive ?
The particles in some GRB jets have been clocked at speeds exceeding 99.
The GRB will enact whatever is required to put this right.
are lead authors on the two accompanying Nature articles, which describe follow-up observations after Swift's detection of GRB 050724.
The research on the association of a GRB with a supernova required great international effort, as it was necessary for telescopes at various observatories to monitor the evolution of the intense brightness over months.
Astronomers think Population III stars ended their lives as blue supergiants, so GRB 130925A might prove to be a valuable nearby analog to phenomena they might one day detect from the universe's most distant stars.
Primary data was collected during our 2008 Mozambique field study, which was part of a larger multi-country research initiative initiated by UNIFEM to investigate the incorporation of GRB into the aid effectiveness agenda (9).
The professor, who joined the university in 1999, said this find was special because until now, most GRBs were distant.
The LAT detected GRB 130427A for about 20 hours, far longer than any previous burst.
The policy, planning and finance departments of all ministries must take the lead on GRB and put in place a coordination mechanism.
Approximately 90 minutes after the outburst, a spectrum was obtained at Gemini-North on Mauna Kea which indicated that the GRB had a redshift Z = 0.
Winfield said of his departure: "It's been a very challenging but enjoyable three years - initially as the independent director on the GRB and, more recently, as chair.
Incredible gamma-ray burst (GRB) called GRB 110328A, observed with NASA's Chandra X-ray Observatory.