GPR19

GPR19

A gene on chromosome 12p12.3 that encodes an orphan G protein-coupled receptor.
References in periodicals archive ?
Omeros Corporation (Nasdaq:OMER), a clinical-stage biopharmaceutical company, said on Wednesday that with its identification of compounds that interact selectively with each of four additional orphan G protein-coupled receptors (GPCRs), namely GPR19, GPR20, GPR31 and GPR141, it has now unlocked over 20% of the 77 Class A orphans.
GPR19 has been tied to metastatic melanoma, the most advanced stage of melanoma, while GPR20 and GPR141 are expressed in areas of the body associated with gastrointestinal disorders and respiratory/immunologic disorders, respectively.