GPR161

GPR161

A gene on chromosome 1q24.2 that encodes an orphan G protein-coupled receptor that plays a role in neurulation and lens development.
References in periodicals archive ?
GPR78 has been linked to bipolar affective disorder and schizophrenia, and GPR161 has been tied to congenital cataracts and birth defects of the brain and spinal cord.
13, 2011 /PRNewswire/ -- Omeros Corporation (NASDAQ: OMER) today reported that it has identified compounds that interact selectively with each of four additional orphan G protein-coupled receptors (GPCRs) - GPR15, GPR39, GPR78 and GPR161.
These statements include, but are not limited to, statements regarding Omeros' expectations regarding its ability unlock orphan GPCRs and add a large number of new drug targets and their corresponding compounds to the market, the multiple new opportunities for drug development that the four unlocked orphan GPCRs present to the pharmaceutical industry, the potential disorders that could be treated by drugs that target GPR15, GPR39, GPR78 and GPR161 and that the Company's success in unlocking the four orphan GPCRs enables the design of novel compounds that could result in new therapies.