GP9

(redirected from GPIX)

GP9

A gene on chromosome 3q21.3 that encodes a surface membrane platelet glycoprotein, which forms a 1-to-1 non-covalent complex with glycoprotein Ib, functioning as a von Willebrand factor receptor. The complete receptor complex consists of alpha subunit, beta subunit (the GP9 product) and platelet glycoprotein V.
References in periodicals archive ?
Most of the genetic defects are due to mutations of the GPIba gene, but may also be due to defects of the GPIbI3 or GPIX genes.
By using PCR, different polymorphic variants of GPIB a together with GPIX were cloned.
The GPIb complex is a heptamer composed of 4 distinct gene products: 2 molecules of GPIb[alpha], 2 of GPIb[beta], 2 of GPIX, and 1 of GPV.
Most of the Bernard-Soulier genetic defects are due to mutations of the GPIb[alpha] gene, but may also be due to defects of the GPIb[beta] or GPIX genes.