GPC1


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GPC1

A gene on chromosome 2q35-q37 that encodes glypican 1, a cell surface proteoglycan with heparan sulfate that contains a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) bond. The GPC family plays a role in controlling cell division and growth regulation.

Molecular pathology
Defects in processing glypican 1 occur in fibroblasts of patients with Niemann-Pick Type C1 disease.
References in periodicals archive ?
In addition, the Medicare Prescription Drug, Improvement, and Modernization Act of 2003 (MMA) further increased the favorable treatment of physicians in lower-cost areas by setting a minimum value of the physician work GPC1 at 1.
From Figure 5, comparing PC1 and GPC1, in the presence of GAC, the lag phase for degradation was significantly lowered from 33 h to 6 h and consequently total degradation time decreased from 42 h to 12 h, or almost 4 times reduction in time taken.