GPBAR1

GPBAR1

A gene on chromosome 2q35 that encodes a G protein-coupled receptor for bile acid. Bile acid binding induces GPBAR1 internalisation, activation of extracellular signal-regulated kinase and intracellular cAMP production; it is believed to be involved in the suppression of macrophage functions by bile acids.
References in periodicals archive ?
Gene symbol Gene name GO biological process TPP ITIH1 Inter-alpha-trypsin Hyaluronan metabolic inhibitor heavy chain 1 process PCK1 Phosphoenolpyruvate Glucose metabolic process carboxykinase 1 FABP4 Fatty acid binding Cholesterol homeostasis 4 protein GPBAR1 G-protein-coupled bile Cell surface bile acid acid receptor 1 receptor signaling pathway PPP1R1A Protein phosphatase 1 Glycogen metabolic regulatory inhibitor process subunit 1A SLC04C1 Solute carrier organic Cell differentiation anion transporter family, member 4C1 FNDC5 Fibronectin type III Response to muscle domain-containing protein activity 5 ADIPOQ Adiponectin.