CSF2

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CSF2

A gene on chromosome 5q23-q31 that encodes colony stimulating factor 2 (granulocyte-macrophage), a cytokine that controls the production, differentiation and function of granulocytes and macrophages.

Molecular pathology
CSF2 is localised to a cluster of related genes at chromosome 5q31, a region associated with deletions in the 5q- syndrome and acute myelogenous leukaemia.
References in periodicals archive ?
pyogenes induced substantial amounts of the pro-inflammatory cytokines IL-6, 1L-8 (CXCL8), MCP-1, GMCSF, GRO[alpha], and smaller but significant amounts of IL-4 and MIP-1[alpha].
The migrated lymphocytes, of which the functions are modulated by the active ingredients of TJ-48 in Peyer's patches, are postulated to regulate the systemic and mucosal immune system through cytokines such as IL-6 and GMCSF.
in Hall A, Abstract: 1346 -- Neutralizing IFN-alpha in SLE affects GMCSF, TNF-alpha, IL-10, IL1-beta and BAFF signaling pathways - Brandon Higgs, Ph.
There was a trend toward improved survival in the combination therapy group as well as a statistically significant correlation between peak GMCSF levels and survival in both treatment groups.