GM2 gangliosidosis

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gangliosidosis /gan·gli·o·si·do·sis/ (gang″gle-o-si-do´sis) pl. gangliosido´ses any of a group of lysosomal storage diseases marked by accumulation of gangliosides GM1 or GM2 and related glycoconjugates due to deficiency of specific lysosomal hydrolases, and by progressive psychomotor deterioration, usually beginning in infancy or childhood and usually fatal.

GM1 gangliosidosis that due to deficiency of lysosomal β-galactosidase activity, with accumulation of ganglioside GM1, glycoproteins, and keratan sulfate.

GM2 gangliosidosis that due to deficiency of activity of specific hexosaminidase isozymes, with accumulation of ganglioside GM2 and related glycoconjugates; it occurs as three biochemically distinct variants, including Sandhoff's disease and Tay-Sachs disease.

G_M2 gangliosidosis

See Tay-Sachs disease.

GM₂ gangliosidosis

see gangliosidosis.

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Alpers' disease Andersen's disease Cherry Spot Dejerine's disease disease ganglioside gangliosidosis GM1 gangliosidosis Kienböck's disease Kinky Hair Disease Köhler's bone disease Krabbe's disease Kufs' disease Tay-Sachs disease			There's a cat model for Sandhoff disease, which is GM2 gangliosidosis. EP interview with Dr. Cynthia Tifft by The Exceptional Parent			glycotropic glycotropic factor glycuresis glycuronate glycyl glycyl alcohol glycylglycine Glycyphagus glycyrrhetinic acid glycyrrhiza Glycyrrhiza glabra glycyrrhizic acid glyoxylate glyoxylic acid Glyoxylide glyphosate Glyptauchen panduratus gm GM-1 gangliosidosis GM-2 GM-2 gangliosidosis GM-CSF gm. GM1 gangliosides GM1 gangliosidosis GM2 gangliosidosis GMA GME Gmelin test Gmelin-Rosenbach test GMENAC GMO GMP GMS stain GN Gn-RH GNA Gnaphalium purpureum gnat gnath(o)- gnath- gnathalgia gnathic gnathic index gnathion gnathitis gnatho- gnathocephalus gnathodynamics gnathodynamometer gnathodynia			GM Hopkins GM Nameplate, Inc. GM technology GM technology GM technology GM technology GM Telekom Service India Private Limited GM tube GM&O GM-1 gangliosidosis GM-2 GM-2 gangliosidosis GM-CFU GM-CSF GM-CSF GM-CSF GM-free GM-J GM-L gm. gm. gm. GM/AHS GM/HBC GM/IVH GM@W GM1 GM1 gangliosides GM1 gangliosidosis GM2 GM2 gangliosidosis GM3 GMA GMA GMAA GMAAC GMAB Gmabit Gmabit Gmabit Gmac GMAC CF GMACA GMACC GMACCM GMACF GMACL GMACP GMACS GMACS16 GMACS32 GMACT GMAD GMADA GMADE GMAE GMAF GMAFB

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