SLC2A2

(redirected from GLUT2)
Also found in: Wikipedia.

SLC2A2

A gene on chromosome 3q26.2-q27 that encodes glucose transporter type 2, a plasma membrane glycoprotein of the liver, islet beta cells, intestine and kidney epithelium, which mediates facilitated bidirectional glucose transport.
References in periodicals archive ?
One mechanism by which A1 beta-casein may contribute to the development of DM-1 relates to the potential molecular mimicry (or cross-reactivity) between beta-casein and an epitope of the pancreatic beta-cell glucose transporter GLUT2, as autoantibodies to GFUT2 have been described in patients with recent-onset DM-1.
Features GK rats Human Insulin response to glucose Decreased Decreased Insulin response to GLP-1 Increased Not determined Glucose oxidation Decreased Decreased GPDH activity Decreased Decreased ATP/ADP ratio Decreased Decreased GLUT2 Decreased Decreased Glucokinase Decreased Decreased IRS-2 Decreased Decreased Pro-insulin/insulin ratio Increased Increased Markers of systemic Increased Increased inflammation Lipid profiles Increased Increased GK: Goto-Kakizaki; GLP-1: glucagon-like peptide-1; CPDH: glycerol-3-phosphate dehydrogenase; ATP: adenosine triphosphate; ADP: adenosine diphosphate; GLUT2: glucose transporter; IRS-2: insulin receptor substrate-2.
Anti-stress Chinese medicine decoction enhance growth performance and intestinal glucose absorption in heat-stressed pigs by up-regulating the expression of SGLT1, GLUT2 mRNA.
Semi-quantitative reverse-transcription PCR for expression levels of GLUT2 and pyruvate kinase coding genes
Sugar absorption in the intestine: the role of GLUT2.
GLUT2 tarafindan alloksana taninan bu serbest giris alloksanin beta hucre spesifitesinin bir sebebidir (10).
Inhibition of the intestinal glucose transporter GLUT2 by flavonoids.
Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels.
In addition to being the major regulator of the insulin gene, Pdx1 also regulates the expression of additional islet-specific genes through its interaction with their promoter regions, which include GLUT2, Nkx6.
Presence and differential expression of SGLT1, GLUT1, GLUT2, GLUT3 and GLUT5 hexose-transporter mRNAs in Caco-2 cell clones in relation to cell growth and glucose consumption.
Then, the accumulated glucose in the enterocytes is transported by GLUT2 (Glucose Transporter 2) located in the basolateral membrane into the blood (Wood and Trayhurn, 2003) with the aid of facilitative diffusion down its concentration gradient.
Fructose absorption by the apical transporter GLUTS requires a concentration gradient, which is maintained both by the active absorption of nutrients and water and by fructose transport out of the enterocytes by the basolateral transporter GLUT2.