SLC2A1

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SLC2A1

A gene on chromosome 1p34.2 that encodes glucose transporter type 1, a key glucose transporter in the blood-brain barrier.

Molecular biology
SLC2A1 mutations cause paroxysmal exertion-induced dyskinesia.
References in periodicals archive ?
This leads to the activation of various HIF-regulated genes, including VEGFR and glucose transporter GLUT1 and increased expression of several glycolytic enzymes.
4] Nonstandard abbreviations: FGF, fibroblast growth factor; FGFR, FGF receptor; FHF, fibroblast homologous factor; SLC2A1, solute carrier family 2 (facilitated glucose transporter), member 1; GLUT1, glucose transporter 1.
This is probably through the enhanced GLUT1 expression via a PKC-dependent mechanism.
Pycnogenol metabolites were found in leukocytes via the GLUT1 transporter in a study earlier this year.
Akt substrate TBC1D1 regulates GLUT1 expression through the mTOR pathway in 3T3-L1 adipocytes.
Ultragenyx is planning to develop other potential indications for UX007, including GLUT1 deficiency syndrome (also known as De Vivo disease), a genetic disorder that impairs brain energy metabolism.
Fields Taylor, three, suffers from GLUT1 deficiency, an incurable genetic disorder which affects her ability to speak.
Fields Taylor, suffers from GLUT1 deficiency, a rare and incurable genetic disorder, which affects her ability to speak, the Mirror reported.
9:30 ALTERATION OF GLUT1 AND GLUT4 IN L6 MUSCLE CELLS IN RESPONSE TO GLUCOSE LEVELS AND INSULIN **, Cameron Medina * and Linda G.
2+]] modulates basal GLUT1 activity and plays a permissive role in its activation by metabolic stress and insulin in rat epithelial cells.
She is one of only 25 people in the UK, and 100 in the world, with GLUT1 deficiency syndrome, which inhibits the body's capacity to process fat.