The beneficial effects induced by PEG 35 are mainly associated with the preservation of the mitochondrial status, as revealed by decreases in GLDH
levels and intravital microscopy findings.
Transformation appeared to be appropriate except for GGT, GLDH, and SDH.
At baseline (t = 0) of all 30 birds, the sample quantity was insufficient to determine concentration CHOL in 15 birds and BA in 7 birds and activities of GLDH in 3 birds and SDH in 1 bird.
At only 1 time point (t = 24) and in only 1 subgroup (B) was the mean GLDH activity significantly different from baseline in group 2.
Because the enzymatic level of the mitochondrial enzyme GLDH did not change significantly, the mitochondrial cell membrane was not damaged, which is caused by severe liver damage.
For coumarin, fasting does not influence the amounts of the measured enzymes such as ALT, ATP, GLDH and LDH.
Contents of alanine aminotransferase (ALT), glutamate dehydrogenase (GLDH), lactate dehydrogenase (LDH) and bile secretion of the isolated perfused rat liver in dependence of a treatment with coumarin and fasting Period of Group perfusion Control with fasting Parameter (min) Control (n = 8) (n = 6) ALT 0 0 0 (U/l perfusate) 30 0 0 60 8 [+ or -] 3 48 [+ or -] 9 90 8 [+ or -] 4 72 [+ or -] 12* 120 20 [+ or -] 11 92 [+ or -] 16* GLDH 0 4.
In all 3 species, ranges for total bile acids were lower in galahs and SC cockatoos, whereas those for GLDH, cholesterol, and amylase were higher than previously reported ranges.
Previously quoted reference ranges of GLDH for cockatoos are psittacine reference ranges,24,25 and some variation between species is expected.