GHB


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GHB

GHB

abbr.
gamma-hydroxybutyrate

glycosylated hemoglobin (GHb/Hb A1c)

[glīkō′silā′tid]
a hemoglobin A molecule with a glucose group on the N-terminal valine amino acid unit of the beta chain. The glycosylated hemoglobin concentration represents the average blood glucose level over the previous several weeks. In controlled diabetes mellitus the concentration of glycosylated hemoglobin is within the normal range, but in uncontrolled cases the level may be three to four times the normal concentration. Assays of Hb A1c, which normally has a 4-month life span, reveal whether glucose levels have been properly controlled during a period of several weeks before the test. The normal range is 1.8% to 4.0% for children; 2.2% to 4.8% for adults. Also spelled glycosylated haemoglobin.

glycosylated hemoglobin (GHb, GHB) test

a blood test used to monitor diabetes treatment. It measures the amount of hemoglobin A1c in the blood and provides an accurate long-term index of the patient's average blood glucose level.

glycosylated hemoglobin (GHb, GHB) test

a blood test used to monitor diabetes treatment. It measures the amount of hemoglobin A1c in the blood and provides an accurate long-term index of the patient's average blood glucose level.

anabolic steroid

A drug or hormone-like substance chemically or pharmacologically related to 17-α-alkylated testosterone that promotes muscle growth, which are commonly abused by athletes. Lipid changes by ASs are more marked with oral stanazol (manufactured for horses) than with IV testosterone; it decreases HDL-C (especially HDL2) and increases hepatic TG lipase (HDL) catabolism.
 
Indications
Children, adolescents with delayed puberty, decreased growth, small penis, hypogonadism, testosterone deficiency, osteoporosis management, aplastic anaemia, endometriosis, angioedema, sports performance enhancement (no longer legal), relief and recovery from common injuries, rehabilitation, weight control, anti-insomnia, and regulation of sexuality, aggression and cognition.

Route
Oral, parenteral.
 
Metabolic effects
Increased protein synthesis and amino acid consumption, androgenesis, catabolism and gluticocototitosis.
 
Adverse effects (men)
Breast enlargement (gynecomastia), testicular atrophy, sterility, sperm abnormalities, impotence, prostatic hypertrophy, myocardial hypertrophy and fibrosis, myocardial infarction and fatal arrhythmias, peliosis hepatis, cholestasis, hepatic adenomas, testicular atrophy, peripheral oedema, intracerebral thrombosis.

Adverse effects (women)
Clitoral hypertrophy, beard growth, baldness, deepened voice, decreased breast size.

Adverse effects (men and women)
Aggression and antisocial behavior, increased risk of cardiovascular disease, peliosis hepatis, haemorrhage, jaundice, acne, accelerated bone maturation resulting in short stature, liver tumours (hepatic adenomas and CA) which may regress with abstinence; AS abusers are at an increased risk for HIV transmission, given the common practice of sharing of needles when injecting ASs.

Lab
ASs are detectable to 1 parts per billion 4 days after last use if the hormone is water-soluble, or 14 days after use in lipid-soluble compounds.

FDA status
ASs are schedule-III drugs per the Controlled Substances Act.

GHB

1. Gamma-hydroxybutyrate, γ-hydroxy-butyrate. See GABA.
2. Glycosylated hemoglobin, see there.

GHb

Glycosylated hemoglobin, see there.

GHB

Abbreviation for gamma (γ)-hydroxybutyrate.

GHB

Abbreviation for γ-hydroxybutyrate.
References in periodicals archive ?
If you have prescription medication you must take on a regular basis, include enough doses in your GHB to last you for your trip home.
GHB counteracts these abnormalities by increasing slow wave sleep, lessening stage 1 sleep, and reducing arousals from rapid eye movement (REM) sleep.
GHB is an acid that occurs naturally in the nervous system, while small amounts can also be found in wine, beef, citrus fruits and animals.
The questionnaire asked about demographics, extent of experience using GHB, ways of acquiring GHB, positive and negative experiences with GHB, and perception of an addiction problem with GHB.
I am obliged to record a narrative verdict that sadly Mr Timney died as a result of the recreational drug use of GHB.
Sheketoff, Patrolman Arroyo's lawyer, that he had in fact sold 20 bottles of GHB that he had received from Mr.
Although Brown made no secret of her GHB use to relatives and friends, Garrison said Brown hid the severity of her addiction.
Bell, 43, offered a bottle of wine and another bottle, which he said contained the drug GHB Nick Johnson, prosecuting, said they declined.
A Drink Spike Detector (DSD) is now available through chemists country wide in the form of a small card that changes colour when it comes in contact with liquid spiked with GHB or ketamine, the two most commonly used and easily obtainable 'date rape' drugs.
GHB first garnered use among body builders, who used the drug's euphoric effects to help with marathon weightlifting sessions.
Sometimes called Georgia Home Boy, liquid ecstasy, or G, GHB slows the central nervous system (brain and spinal cord), causing a sedative effect.