corneal dystrophy, gelatinous drop-like

(redirected from GDLD)
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corneal dystrophy, gelatinous drop-like

An autosomal recessive disorder (OMIM:204870) characterised by severe corneal amyloidosis leading to blindness.

Clinical findings
In the first decade of life: blurred vision, photophobia and foreign-body sensation; by third decade, raised, yellowish-grey, gelatinous masses severely impair visual acuity, and lamellar keratoplasty is required.

Molecular pathology
Caused by defects of TACSTD2, which encodes a cell surface receptor.