GUCY1B3

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GUCY1B3

A gene on chromosome 4q31.3-q33 that encodes a beta subunit of a soluble guanylate cyclase, one of a family of nitric oxide-activated heterodimeric enzymes that catalyse the conversion of GTP to 3’,5’-cyclic GMP and diphosphate. GUCY1B3 serves as the main receptor for nitric oxide (NO) and nitrovasodilator drugs.