NR3C1

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NR3C1

A gene on chromosome 5q31.3 that encodes a glucocorticoid receptor, which acts as either a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, or as a regulator of other transcription factors.

Molecular pathology
NR3C1 mutation are associated with generalised glucocorticoid resistance.
References in periodicals archive ?
The GCR further noted that the Competition Appellate Tribunal began hearing appeals against the Commission's orders last year - and much to the delight of the CCP, the tribunal upheld many of its decisions.
La mayor parte de los estudios ejecutados sobre modificacion de mezclas asfalticas con GCR han sido realizados sobre mezclas de concreto asfaltico o del tipo denso y en caliente.
The construction companies have offered financial settlements which all claimants represented by UCATT, GMB and GCR have now accepted.
Furthermore, the group's capital base is deemed adequate to absorb potential termination and/or credit losses under our business stress scenario, said GCR.
One country that was ranked in the top 30 in 2012 and 2013 but not covered in the 2014 GCR was Brunei Darussalam, because according to the WEF the 2014 survey of business executives in this country (and two other countries, Benin and Liberia) was "not completed to minimum requirements.
The GCR Leaders Symposium will take place at the Marina Bay Sands, ahead of the ICT/Cafe Asia event.
Granic's aim is to fulfil the needs of plastics converters regarding plastic reinforcement, oil-based polymer replacement, lowered environmental impact, carbon footprint reduction (through certification), reduced energy consumption and help converters achieve a reduction in the cost of their finished goods," commented Victor Oliva, Commercial Director at GCR.
Therefore, having considered the prestige of the GCR we must pay close attention to really understand the real picture behind this development.
GCR has reaffirmed Central Africa Building Society's ("CABS"), long term domestic Zimbabwean rating of A+ (single A plus).
Columbia's GCR customers will see the new term on their bills, but nothing else will change.
For a better understanding of the phenomenon, the researchers examined GCR formation in chromosome regions in yeast (Saccharomyces cerevisiae).
GCR lowers ink consumption by up to 25%, depending on image content.