Following this case of GBS disease
, the hospital implemented a universal screening strategy While universal screening increases costs for cultures and antibiotic treatment, cost analyses show that only 8% more women are treated with antibiotics with universal screening than with risk-based screening.
The reasons for differences in rates of GBS disease
between countries may include demographic differences, socioeconomic factors, and variations in clinical practices, such as the frequency of taking blood cultures in diagnostic examinations.
These new findings suggest that further declines in early-onset GBS disease
could result if physicians fully embraced the guidelines.
Therefore, we set out to further characterize GBS disease
in Blantyre District in Malawi.
Although the incidence of GBS disease
has declined substantially, it remains the leading cause of serious infection in newborns (1).
Premature infants are at highest risk for severe GBS disease
Since its emergence in the 1970s, GBS disease
has been the leading invasive bacterial infection associated with illness and death among newborns in the United States.
As a result, the Centers for Disease Control have stated that "intrapartum chemoprophylaxis is not a permanent or comprehensive strategy for GBS disease
prevention," and that "further work on GBS vaccine development is warranted.
In multivariate analysis, the risk for early-onset GBS disease
in the screening cohort was less than half that seen with the risk-based method (relative risk 0.
In the UK, early onset GBS disease
(within the first six days and usually within the first 24 hours from birth) affects around 400 babies a year.
early onset GBS disease
affects around 400 babies a year.
Jane Plumb, chief executive of Group B Strep Support, says: "It's In the UK, early onset GBS disease
AROUND a quarter of pregnant women unknowingly carry a bacterial infection that can kill their newborn baby.