adiponectin

(redirected from GBP28)
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ad·i·po·nec·tin

(ad'i-pō-nek'tin),
Protein hormone produced and secreted by adipocytes into the systemic blood circulation; causes sensitivity of peripheral tissues to insulin.
[adipo- + L. necto, to fasten, + -in]

adiponectin

(ăd′ə-pə-nĕk′tĭn)
n.
A polypeptide hormone that is secreted by fat cells and regulates glucose and lipid metabolism, especially by increasing insulin sensitivity and muscle uptake of glucose and by decreasing glucose production in the liver.

Adiponectin

A circulating protein encoded by ADIPOQ on chromosome 3q27, which is secreted exclusively by mature adipocytes. It is a key adipokine in the control of fat metabolism and insulin sensitivity, and has direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. It stimulates AMPK phosphorylation and activation in the liver and skeletal muscle, enhancing glucose utilisation and fatty acid hydrolysis. It antagonises TNF-alpha by down-regulating its expression in the liver, macrophages and elsewhere, and by counteracting its direct effects. It inhibits endothelial NF-kappa-B signalling by a cAMP-dependent pathway. It may play a role in cell growth, angiogenesis and tissue remodelling by binding and sequestering various growth factors with distinct binding affinities, depending on complex size—low, medium, or high molecular weight.

ad·i·po·nec·tin

(ad'i-pō-nek'tin)
Protective adipokine that reduces lipid accumulation and endothelial adhesion resulting from vascular injury; increases skeletal muscle oxidation of free fatty acids; reduces hepatic glucose output; increases peripheral insulin sensitivity.
[adipo- + L. necto, to fasten, + -in]

adiponectin

A cytokine derived from adipose tissue that has antidiabetic and antiatherosclerotic properties.
References in periodicals archive ?
As part of the offer, British Airways will operate services to Bordeaux, Gatwick's popular route with flights from GBP28 each-way, while Gatwick's new route to Limoges, which launched in May this year, is also on offer from GBP35 each-way.
Part of the British government backed financial services provider Lloyds Banking Group (LSE:LLOY) Halifax on Friday reported that those who have yet to put any money aside for Christmas will need to start saving GBP28 a week between now and Christmas to make sure they have enough to cover the cost.
30 November 2011 - Citigroup has resumed coverage of the stock in Anglo-Swedish pharma major AstraZeneca plc (LON:AZN; STO:AZN) with a "neutral" recommendation and a GBP28 share price target.
Adiponectin, also called Acrp30, GBP28, apM1 or AdipoQ, was identified first by Scherer in 1995 (Scherer et al.
According to The Associated Press, the carrier revealed that it lost GBP28.
Title: Kosmos Author: Adam Bartos Published by: Princeton Architectural Press ISBN: 1-56898-308-5 Price: GBP28 Reviewer: Darren Ingram
NEA No: 03628, ISBN: 92-64-09782-1, OECD Ordering reference number: 662002093P1Price: USUSD 40, GBP28, 5150.
Over the half year to the end of September, PSINet Japan recorded turnover of GBP28 million (Euro 45 million).
Paul Boateng, Chief Secretary to the Treasury for the Government of the United Kingdom, in videotaped remarks to the Visa conference today, cited UK National Audit Office approved figures that indicate efficiency savings of GBP28 (US$50) for every transaction made using the Government Purchasing Card (GPC) program, as well as environmental savings of 1 million pieces of paper per month.
Adequate Liquidity: At FYE17, TCG had sufficient liquidity, comprising GBP374 million of readily available cash (Fitch views GBP1 billion as restricted for seasonal working-capital purposes, and also excludes GBP28 million for cash held in escrow accounts and at the group's captive insurance companies).
The BoE said that it had halved the total purchases of UK gilts overseas in March from the 33-year record of GBP28.
The current gate charge in US is around GBP28 per bag, and is applicable to bags that do not fit underneath a passenger seat, and have to be put inside the aircrafts overhead bin.