PMP22

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PMP22

A gene on chromosome 17p12 that encodes an integral membrane protein which is a major component of myelin in the peripheral nervous system, and appears to be involved in growth regulation and myelinisation of the peripheral nervous system.

Molecular pathology
PMP22 mutations are linked to Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome and hereditary neuropathy with liability to pressure palsies.
References in periodicals archive ?
GAS3 is a distributed quasi steady-state real-coded genetic algorithm.
GAS3 uses sex determination method (SDM) to determine the sex (male or female) of members in population.
This Section also gives comparison of GAS3 with other real-coded genetic algorithm and evolutionary strategy proposed in literature.
GAS3 is a distributed quasi steady-state genetic algorithm with species and sexual selection scheme.
This is a generalized framework for GAS3, where one can use his own sex determination method, species evolution scheme, four plans for evolution and scheme for merging of species.
In GAS3, we restricted mating in species only and no inter-species mating is allowed.
GAS3 evaluates performance of each species after certain number of generations and the species not performing well are merged into nearest species (similar in phenotype).
GAS3 is a generalized model; hence one can use his own sex determination method, species evolution scheme, four plans for evolution and scheme for merging of species.
The experimental results of GAS3 with test function show that, its performance on unimodal and multi-modal functions strongly depends on value of R.
The characteristic parameter R allows GAS3 to design two different kinds of specialization algorithms.
A graduate of the Engineer Captain 's Career Course, GAS3, and Northern Warfare School, CPT Judson holds a bachelor's from the University of Maine and is working on a master's in business administration at Regis University.