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GALOP Syndrome

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GALOP Syndrome
A cerebellar disorder characterised by the acronym, GALOP:

Gait ataxia
Autoantibodies IgM GD1a autoantibody against central myelin antigen
Late age of Onset
Polyneuropathy, sensory > motor, symmetric
Management Cyclophosphamide, human Ig

GALOP syndrome
Neurology A cerebellar disorder characterized by the acronym, GALOP: Gait disorder–ataxia, Autoantibodies–IgM against central myelin antigen; Late age of Onset; Polyneuropathy, sensory > motor, symmetric Management Cyclophosphamide, human Ig


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7,8) identified a subgroup of older patients with peripheral neuropathy, gait ataxia, and elevated titers of serum immunoglobulin M (IgM) binding to galopin and used the term GALOP syndrome (Gait disorder, Antibody, Late-age Onset, Polyneuropathy) to delineate common features among these patients.
Abstract: An elderly woman complaining of a gait disorder was found to have the GALOP syndrome (gait ataxia, late-onset polyneuropathy).
 
 
 
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