benzodiazepine receptor

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benzodiazepine receptor

Any of a number of different receptors for benzodiazepine identified in the brain. BZ-1 receptors may affect neural pathways involved in normal sleep patterns, while BZ-2 receptors are involved in memory and motor functions.
References in periodicals archive ?
A major inhibitory synaptic receptor is the hetero-pentameric GABAA Receptor (GABAAR), which is stabilised in the synapse by the intracellular scaffolding protein gephyrin.
Prediction of GABAA receptor proteins using the concept of Chou's pseudoaminoacid composition and support vector machine.
Anxiogenic effects of neurosteroid exposure: sex differences and altered GABAA receptor pharmacology in adult rats.
As a benzodiazepine, alprazolam exerts its pharmacological actions by binding to the GABAA receptor in the central nervous system and potentiating its neuroinhibitory effects.
The ingredient BluCetin-DHM, which is derived from Hovenia dulcis (oriental raisin tree), can be used as a hangover remedy as a result of the discovery of dihydromyricetin (DHM), a unique natural molecule that targets the GABAA receptor in the brain and has been seen to reduce the negative effects of drinking in excess.
This GABAA receptor consists of five subunits, and studies have found that certain alleles of several subunit genes can influence the risk for alcoholism and other addictions, as well as of conduct disorder symptomology and can modify electrophysiological traits related
Findings showed significant associations for GABAA receptor polymorphisms, in particular the A4 subunit and gene x gene interaction between receptor subunits (Ma et al.
Lacorazza they found that when the cells were exposed to secretions from the bacteria, they exhibited increased expression of the GABAA receptor in the immune cells.
This study was designed to determine whether the GABAA receptor activation and/or the suppression of pro-inflammatory cytokines mediate baicalin induced sleep alterations.
In one study of guinea pigs repeatedly exposed to high ethanol concentrations throughout pregnancy, researchers found persistent alterations in GABA transmission (see table 1) and increased levels of certain GABAA receptor subunits ([[alpha].
Consistently, Kimura (1994) showed that intravenous infusion of bicuculline, a GABAA receptor antagonist, on the morning of proestrus induced a premature surge-like secretion of LH (23).