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G6PD deficiency |
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Glucose-6-phosphate dehydrogenase (G6PD) deficiency An inherited disorder in which the body lacks an enzyme that normally protects red blood cells from toxic chemicals. When people with this condition take certain drugs, their red blood cells break down, causing anemia. This may also happen when they have a fever or an infection. The condition usually occurs in males. About 10% of black males have it, as do a small percentage of people from the Mediterranean region. Mentioned in: Jaundice, Urinary Anti-Infectives G6PD deficiency, abbreviation for glucose-6-phosphate dehydrogenase deficiency. G6PD deficiency Glucose-6-phosphate dehydrogenase deficiency, see there How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Previously, underlying defects in host defense, especially of neutrophils, have been hypothesized to predispose to infection: cases have been reported in patients with chronic granulomatous disease (13) and G6PD deficiency (14). However, in view of the overlap between malaria, quinine administration, and G6PD deficiency, the hemoglobinuria triggered by this deficiency should not be seen as a separate syndrome (10). |
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