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G6PD |
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G6PD glucose-6-phosphate dehydrogenase.
glucose-6-phosphate dehydrogenase (G6PD) deficiency, an inherited disorder characterized by red cells partially or completely deficient in G6PD, an enzyme critical in aerobic glycolysis. A sex-linked disorder, the defect is fully expressed in affected males despite a heterozygous pattern of inheritance. The disorder is associated with episodes of acute hemolysis under conditions of stress or in response to certain chemicals or drugs. The anemia that results is a kind of nonspherocytic hemolytic anemia. See also congenital nonspherocytic hemolytic anemia, favism. glucose-6-phosphate dehydrogenase (G6PD) test, a blood test to diagnose G6PD deficiency in suspected individuals. Deficiency of this enzyme causes precipitation of hemoglobin and cellular membrane changes, possibly resulting in hemolysis of variable severity, a sex-linked trait carried on the X chromosome. G6PD glucose-6-phosphate dehydrogenase. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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