CCNE1

(redirected from G1/S-specific cyclin-E1)

CCNE1

A gene on chromosome 19q12 that encodes cyclin E1, which forms a complex with and acts as a regulatory subunit of CDK2. Cyclin E1 is required for cell cycle G1/S (start) transition; it accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. It is highly expressed in the testes and placenta.