CX3CR1

(redirected from G-protein coupled receptor 13)

CX3CR1

A gene on chromosome 3p21.3 that encodes a G protein-coupled receptor for fractalkine, a transmembrane protein and chemokine involved in leukocyte adhesion and migration. CX3CR1 is also a coreceptor for HIV-1; some alternatively spliced forms of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS.
References in periodicals archive ?
Fractalkine is an immune regulatory factor that sends signals via the CX3CR1 receptor, also called G-protein coupled receptor 13 (GPCR13).

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