G-protein


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Related to G-protein: Adenylyl cyclase

G pro·teins

intracellular membrane-associated proteins activated by several (for example, β-adrenergic) receptors; they serve as second messengers or transducers of the receptor-initiated response to intracellular elements such as enzymes to initiate an effect. These proteins have a high affinity for guanine nucleotides and hence are named G proteins.

G-protein

(jē′prō′tēn′, -tē-ĭn)
n.
Any of a class of cell membrane proteins that transmit signals from certain receptors to effector enzymes, enabling the cell to regulate its metabolism in response to hormones and other extracellular stimuli.
References in periodicals archive ?
Characterization of G-protein alpha subunits in the Gq class: expression in murine tissues and in stromal and hematopoietic cell lines.
The report provides a snapshot of the global therapeutic landscape for Sphingosine 1-Phosphate Receptor 1 (S1P Receptor 1 or Endothelial Differentiation G-Protein Coupled Receptor 1 or Sphingosine 1-Phosphate Receptor Edg-1 or CD363 or S1PR1 or CHEDG1 or EDG1)
sup][12],[13] One commonly studied candidate gene for EH is G-protein [sz]-polypeptide 3 gene ( GNB3 ).
Human G-protein [beta]3 subunit variant is associated with serum potassium and total cholesterol levels but not with blood pressure.
Many forms of cellular communication rely on G-protein linked signaling pathways to amplify the intracellular effects of certain molecules.
Under the terms of the agreement, DanioLabs will use their proprietary IBD model to screen compounds from Oxagen's G-protein coupled receptor (GPCR) program.
Similarly, a third variation on ATP use involves switching the G-protein on and off.
We are currently investigating the functional link of G-protein activation to regulation of ecdysteroidogenesis.
This report analyzes the Global market for G-Protein Coupled Receptors (GPCRs) in US$ Billion.
Global Markets Direct's, 'Atypical Chemokine Receptor 3 (Chemokine Orphan Receptor 1 or G-Protein Coupled Receptor 159 or G-Protein Coupled Receptor RDC1 Homolog or GPR159 or CXCR7) - Pipeline Review, H1 2016', provides in depth analysis on Atypical Chemokine Receptor 3 (Chemokine Orphan Receptor 1 or G-Protein Coupled Receptor 159 or G-Protein Coupled Receptor RDC1 Homolog or GPR159 or CXCR7) targeted pipeline therapeutics.
The applicant hypothesises that reproductive hormones and their metabolites play an integral role in beta-cell adaptation in pregnancy through altered nuclear farnesoid-X-receptor (FXR) and G-protein coupled receptor TGR5 activity in the enteroendocrine L-cells and pancreatic islets.
Olefsky and colleagues eventually narrowed their focus to a G-protein receptor called GPR120, which is found only on pro-inflammatory macrophages in mature fat cells.