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G-CSF |
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G-CSF granulocyte colony-stimulating factor. G-CSF, abbreviation for granulocyte colony-stimulating factor. G-CSF granulocyte-colony stimulating factor. G-CSF Granulocyte colony-stimulating factor Molecular therapeutics A biological response modifier, the recombinant DNA form of which is filgrastim–Neupogen® Activity G-CSF stimulates granulocyte production in BM
suppressed by chemotherapy, RT, serving to ↓ infections in Pts with malignancy; G-CSF can induce terminal maturation of myeloid leukemia cell lines and suppress self-renewal, and is thus useful in Pts with AIDS or leukemic relapse after
allogeneic BMT Adverse effects Nausea, bone pain, rash. See Biological response modifiers, Colony-stimulating factors. Cf GM-CSF. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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In the series of in vitro experiments, CD34- positive haematopoietic stem cells enriched from umbilical cord blood were cultured with a medium containing Apollo's fully G-CSF and SCF (granulocyte-colony stimulating factor and stem cell factor) with the same proteins produced from bacteria by competitors. Human G-CSF is a glycoprotein which regulates the production and release of functional neutrophils from the bone marrow. The patient was neutropenic; G-CSF was continued, and she was given cefipime and gentamicin. |
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