CXCR6

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CXCR6

A gene on chromosome 3p21 that encodes a member of the G protein-coupled receptor family which is a receptor for chemokine CXCL16 and a coreceptor for strains of HIV-2 and m-tropic HIV-1.
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The company is using its large portfolio of patented G protein-coupled receptor targets to design improved drugs and to map biological pathways that may offer new ways to treat diseases.
Alpha adrenergic receptors are G Protein-Coupled Receptors that are activated by the neurotransmitter norepinephrine (noradrenaline).
Secret in Receptor Dimerization: A Possible Functionally Important Paradigm for Family B G Protein-Coupled Receptors
ATP has a dual role as both an energy source for enzymatic reactions and as a first messenger for several classes of G protein-coupled receptors and ligand-gated ion channels.
NYSE:PFE) for a subscription to the first database of information on the expression and localization of G protein-coupled receptors (GPCRs) in normal and pathological human tissues.
The new TGEM(TM) Rat Models include tumor suppressors, G protein-coupled receptors, and serotonin receptors.
Two experts, one from academia, the other from industry, provide an accessible summary of the current knowledge in the fast evolving field of G protein-coupled receptors (GPCRs).
G protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellular signals into intracellular reactions ranging from cell-cell communication processes to physiological responses.
La Jolla, CA) has patented newly identified mammalian taste-cell-specific G Protein-Coupled Receptors and the genes encoding said receptors.
The contributors of these 16 papers use disease-oriented methods to describe the physiological roles of G protein-coupled receptors (GPRs) and their roles in target selection, screening and functional arrays.
This report focuses on the intensely studied and highly druggable target class known as G protein-coupled receptors (GPCRs).
Contributors identified only by name offer clues to drug designers on designing ligands that will target G protein-coupled receptors, which comprise over 60% of all that receptors, and so should not be all that hard to hit.

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