fipronil(redirected from Frontline (medicine))
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A phenylpyrazole parasiticide agent that is available as pourable topical solution and spray for flea and tick infestation in dogs and cats; mechanism of action is to disrupt chloride passage through gamma amino butyric acid-mediated channels in nerve cell membranes, resulting in terminal neurologic malfunction. Commercial solutions are flammable.
a reversible GABA-receptor inhibitor that acts on the nervous system of insects. Used topically in flea control programs.