DACT1

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DACT1

A gene on chromosome 14q23.1 that encodes a protein which upregulates DVL2-mediated signalling pathways during development. DACT1 binds to DVL2 and impedes CTNNB1/beta-catenin degradation, thereby enhancing transcriptional activation of target genes of the Wnt signalling pathway.
References in periodicals archive ?
Frodo, named after the Lord of the Rings character, was rescued by the RSPCA.
It is beyond doubt that Tolkien was fully conscious of the weight of these references when he changed his hero's name from Bingo to Frodo.
The others cast themselves down upon the fragrant grass, but Frodo stood awhile lost in wonder.
Flame-haired Ed reckons they'd look like an odd couple from The Hobbit - casting himself in the role of Frodo Baggins.
It is a fairytale nale to a story that started in October 2012 when Ayla and her mum Joanne A Forster, from Cote Hill Riding Centre, bought a newly backed, very green Connemara cross oroughbred pony called Frodo Baggins.
At a deeper level, these main characters, Aragorn, Gandalf, and Frodo, embody the qualities of the three persons of the Holy Trinity, Father, Son, and Holy Spirit.
Though clearly best known throughout the world for his indelible work as Frodo in "The Lord of the Rings" trilogy, Wood has spent a significant portion of his career over the past two decades toiling in edgy films that benefitted from his willingness to tackle tough characters in complex stories.
Individual topics include examinations of the unhealed wounds of Frodo Baggins, incorporeality and transformation, Frodo's body luminality, health and ecology in the context of war; orc bodies' relationship with perversion and redemption, female bodies and femininities, a body of myth representing Sauron, Tolkien and the female bodies, the gifting economy of Middle-earth; and physicality in The Hobbit.
Courageous canines Frodo Baggins, Sherlock and Flag have already completed the West Highland Way without leads.
Who played Frodo Baggins in Peter Jackson''s Lord Of The Rings trilogy?
The chapter (chapter 8 of Book VI, published in 1955 in The Return of the King), in which Frodo and his three hobbit-friends, Sam, Merry, and Pippin, return to overthrow the unjust order that has imposed itself on their homeland while they were absent, has a distinct quality to it.
Melbourne, Jan 10 (ANI): Elijah Wood will revisit his role as Frodo in the upcoming big screen version of 'The Hobbit' despite his character not featuring in the book by J.