DACT1

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DACT1

A gene on chromosome 14q23.1 that encodes a protein which upregulates DVL2-mediated signalling pathways during development. DACT1 binds to DVL2 and impedes CTNNB1/beta-catenin degradation, thereby enhancing transcriptional activation of target genes of the Wnt signalling pathway.
References in periodicals archive ?
Flame-haired Ed reckons they'd look like an odd couple from The Hobbit - casting himself in the role of Frodo Baggins.
It is a fairytale nale to a story that started in October 2012 when Ayla and her mum Joanne A Forster, from Cote Hill Riding Centre, bought a newly backed, very green Connemara cross oroughbred pony called Frodo Baggins.
At a deeper level, these main characters, Aragorn, Gandalf, and Frodo, embody the qualities of the three persons of the Holy Trinity, Father, Son, and Holy Spirit.
Verlyn Flieger's insightful lead chapter, "The Body in Question: The Unhealed Wounds of Frodo Baggins," proposes to show that "[w]hat happens to Frodo's body over the course of his journey is the outward manifestation of his changing inner condition" (12).
Individual topics include examinations of the unhealed wounds of Frodo Baggins, incorporeality and transformation, Frodo's body luminality, health and ecology in the context of war; orc bodies' relationship with perversion and redemption, female bodies and femininities, a body of myth representing Sauron, Tolkien and the female bodies, the gifting economy of Middle-earth; and physicality in The Hobbit.
Courageous canines Frodo Baggins, Sherlock and Flag have already completed the West Highland Way without leads.
Who played Frodo Baggins in Peter Jackson''s Lord Of The Rings trilogy?
The chapter (chapter 8 of Book VI, published in 1955 in The Return of the King), in which Frodo and his three hobbit-friends, Sam, Merry, and Pippin, return to overthrow the unjust order that has imposed itself on their homeland while they were absent, has a distinct quality to it.
Melbourne, Jan 10 (ANI): Elijah Wood will revisit his role as Frodo in the upcoming big screen version of 'The Hobbit' despite his character not featuring in the book by J.
The joey, named Frodo, was found on 5th November in the Sunshine Coast hinterland, with 15 shotgun pellets lodged in her head and body, an Australia Zoo spokeswoman said.
Frodo assembles a special fellowship to embark on a dangerous quest to destroy the ring before it falls into the wrong hands and is used for evil.
FELLOWSHIP OF THE RING (PG) 11am Peter Jackson's enthralling trilogy opens with young hobbit Frodo Baggins (Elijah Wood) roping in a motley crew for a dangerous trip through Middle Earth to destroy a magic ring