Freund's adjuvant


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Related to Freund's adjuvant: Freund's incomplete adjuvant

Freund's adjuvant

(froindz)
n.
A substance consisting of killed microorganisms, such as mycobacteria, in an oil and water emulsion that is administered to induce and enhance the formation of antibodies.

Freund's adjuvant

An emulsion of killed bacteria in oil that induces antibody formation. (Jules Thomas Freund, 1890–1960, Hungarian-born American bacteriologist).
References in periodicals archive ?
Complete Freund's adjuvant (CFA, sigma) was prepared by suspending heat-killed BCG in liquid paraffin at 10mg/ml.
1 mL complete Freund's adjuvant (CFA) (Sigma-Aldrich) into the right hindpaw as in previous studies (Anagnostou 2009, Tigka 2005).
Freund's adjuvant and its incomplete form: Another conventional adjuvants include complete Freund's adjuvant (CFA) and incomplete Freund's adjuvant (IFA).
The protein was diluted 1:1 in complete Freund's adjuvant for the first injection and in incomplete Freund's adjuvant for the subsequent injections.
The animal models included those with neuropathic pain induced by ligation of the Sciatic nerve and those with inflammatory pain induced by the injection of Complete Freund's Adjuvant into the animal's footpads.
with an emulsion form of Candida albicans surface mannan extract (SM) mixed with either Incomplete Freund's Adjuvant [SM/IFA], or Complete Freund's Adjuvant [SM/CFA] or GA mixed with IFA [SM/GA/IFA].
In animal models of neuropathic pain, ralfinamide has demonstrated a strong anti-nocicpetive effect, by a) dose-dependently reducing licking time (formalin test in mice), b) decreasing mechanical allodynia and thermal hyperalgesia (complete Freund's adjuvant test in rats), c) increasing mechanical allodynia threshold (chronic spinal nerve ligation test in rats and chronic constriction injury model in rats).
The bands were dried and homogenized in complete Freund's adjuvant for the first dose and in incomplete adjuvant for the subsequent three weekly doses.
Female BALB/c mice (7-8 weeks of age) were immunized by subcutaneous injection of 30 [micro]g of bovine S100B emulsified in complete Freund's adjuvant.