Fraser syndrome


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Fra·ser syn·drome

(frā'zĕr), [MIM*219000]
an association of cryptophthalmos with multiple anomalies, including middle and outer ear malformations, cleft palate, laryngeal deformity, displacement of umbilicus and nipples, digital malformations, separation of symphysis pubis, maldevelopment of kidneys, and masculinization of genitalia in females; autosomal recessive inheritance.

Fra·ser syn·drome

(frā'zĕr sin'drōm)
An association of cryptophthalmus with multiple anomalies, including middle and outer ear malformations, cleft palate, laryngeal deformity, displacement of umbilicus and nipples, digital malformations, separation of symphysis pubis, maldevelopment of kidneys, and masculinization of genitalia in females; autosomal recessive inheritance.

Fraser,

George R., English geneticist, 1932–.
Fraser syndrome - an association of cryptophthalmus with multiple anomalies. Synonym(s): cryptophthalmus syndrome
Fraser syndrome - see under Melnick, M
References in periodicals archive ?
Furthermore, triploidies, several syndromes (such as Fraser syndrome, and Smith-Lemi-Opitz syndrome), congenital heart defects, cleft lip and palate, neural tube defects, and anorectal malformations have also been described in combination with hypospadias.
In his new autobiography, Hard Knocks And Soft Spots, Paddy has also revealed how he and Roseanne have lost four babies - three girls and a boy - to the rare genetic disease Fraser syndrome.
After having five healthy children, their next four died from a genetic disorder called Fraser syndrome.
This case reports only the second case of Fraser Syndrome (FS) in the dental literature, and the first with hypodontia and shortened roots.
Fraser syndrome is a rare syndrome which is more frequent in consanguineous parents.
The present case is the first report to describe hypodontia and shortened roots in Fraser syndrome.
Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein.
The Fras1/Frem family of extracellular matrix proteins: structure, function, and association with Fraser syndrome and the mouse pleb phenotype.
Fraser syndrome (cryptophthalmos-syndactyly syndrome): a review of eleven cases with postmortem findings.
Clinical manifestations and oral findings in Fraser syndrome.
Fraser syndrome with renal agenesis in two consanguineous Turkish families.
They died when they were just babies, after Paddy and Roseanne discovered they suffered from a condition called Fraser syndrome, a rare genetic condition which is almost always fatal.
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