Fc fragment (redirected from Fragment crystallizable region)

Fc fragment (f-s)

n.

The portion of an immunoglobulin molecule that can be crystallized.

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Fc fragment

a portion of an immunoglobulin molecule, produced by papain digestion, with parts of two heavy chains. It has no antigen-combining sites, but contributes to a number of effector functions such as the binding of antibody to Fc receptors on a variety of cells, the transfer of antibody from the circulation into colostrum, the transfer across the gut of the newborn, and the binding of complement.